What’s New

Our oxLDL test continues to be used in studies of atherosclerosis and resulting diseases and continues to provide measurements that correlate with disease state, making prognosis more accurate. Most recently, Cheng-Hsien Lu et.al. (ref.1) have found a strong relationship between oxLDL levels and stroke outcome in patients admitted with acute ischemic stroke. The stroke patients were found to have a significantly higher oxLDL level which was lowered with statin therapy. The authors conclude “assay of plasma Ox-LDL should be added as a predictor among the panel of conventional biomarkers in stroke outcome“. More recently, Anxin Wang has reported (ref. 2) that the ratio of oxLDL (measured with the 4E6 antibody) to HDL was a powerful indicator of recurrent stroke in patients with mild stroke or transient ischemic attack. More about the role of oxLDL in predicting stroke can be found in the Notebook section here.

1. Tsai, N-W; Lee, L-H; Huang, C-R; Chang, W-N; Chang, Y-T; Su, Y, J; Chiang, Y-F. Critical Care 2014, 18, R16
2. Wang, A;Li, S; Zhang, N; Dai, L; Zuo, Y; Wang, Y; Meng, X; Wang, Y. Stroke. 2018, 49, 2637